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of preferential binding of SYBR Green I to specific DNA fragments in realtime multiplex PCR, Nucleic Acids Research, p.136
·Titli et al, 2018, Significance of circulatory DPP4 activity in metabolic diseases, IUBMB life, pp.112-119
·Sobierajska et al, 2014, Protein disulfide isomerase directly intera
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Identification of Rac-Induced Phosphorylation Sites
Ras gene
Ras와 암과의 연관성
Post-translationl modificaton과 발암원성
Ras 활성 조절의 upstream 및 downstream 단백질
전망
Ⅴ. Rb
What is Retinoblastoma(망막아세포종)?
Signs & Symptoms of Rb
Genetics of Rb
If a parent had
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of Coding Sequences in the Immune System
- The immune system of vetebrates is designed to offer a selective defense against all possible infectious agents, and to be ready even against those that appear on earth in the future.
- How ?
- Several million different protein molecules, immunoglobins or
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in/out 방법
-configuration 방법
-gene highlighting 방법
4)ENCODE, GTEx
-ENCODE project
-ENCODE tract
-GTEx project
-GTEx tract
5)RB1이란
6) ① GENCODE v32 Track
② GTEx tract의 GTEx Gene V8 tract
③ OMIM tract의 OMIM Genes Track
Ⅱ. Method
-UCSC 사용 방법 및 절차
Ⅲ. Result
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in all plant species. Arabidopsis thaliana
② Hygromycin phosphotransferase(hph)
③ Acetyltransferase - gentamycin resistance
④ Dihydrofolate reductase (DHFR)
- DHFR은 methotrexate에 의해 blocking
- mutant mouse에서 methotrexate에 대해 500배 정도 낮은 affinity를 지닌
DHFR을 구해 CaMV 35S prom
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단백질을 만들어내는 것도 가능하고, 이는 pharmaceutical 산업의 요구를 충족시킬 수 있도록 할 것이다. N-glycosylation in ER
type of plant N-glycans
식물 N-glycan의 합성
식물 system에서의 재조합 glycoprotein의 발현
식물 N-glycosylation의 Humaniztion
Plant N-g
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of the UreE accessory protein. J. Bacteriol. 185, 4787-4795.
7. Bury-Mone', S., Skouloubris, S., Labigne, A., De Reuse, H., 2001a. The Helicobacter pylori UreⅠ protein: role in adaptation to acidity and identification of residues essential for its activity and for activation. Mol. Microbiol. 42, 10
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of human telomerase reverse transcriptase
(hTERT) influences telomere lengths during human development.
Int J Cancer 2001, 91:644-649.
5. Hiyama E, Hiyama K, Yokoyama T, Shay JW: Immunohistochemical
detection of telomerase (hTERT) protein in human cancer tissues
and a subset of cells in normal tissu
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Expression of HBsAg in different organs and different plants of
same line
방법: Cherry tomatillo (Physalis ixocarpa Brot.)를 Agrobacterium
tumefaciens를 이용하여 형질전환 후 생성되는 부위별 total antigen
protein량 측정
블라블라...
7. Future study
\\\"More important, food vaccines mig
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