코아 해부학 요약

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코아 해부학 요약에 대한 보고서 자료입니다.

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is responsible for the filtration function of the spleen. The white pulp consists of aggregates of lymphoid tissue and is responsible for the immunological function of the spleen:
b) Red pulp
There is a complex system of blood vessels within the red pulp arranged to facilitate removal of old or damaged red blood cells from the circulation. A small proportion of the splenic blood flow passes through more rapidly without undergoing this process of filtration.
c) White pulp
The white pulp contains T cells, B cells and accessory cells. There are many similarities with lymph node structure. The purpose of the white pulp is to mount an immunological response to antigens within the blood. The white pulp is present in the form of a periarteriolar lymphoid sheath. This sheath contains B cell follicles and T cells. At the edge of the T zone is a region known as the marginal zone where larger lymphocytes and antigen presenting dendritic cells are located.
5) 기타 임프 조직
tonsil(편도) : 입과 코를 통하여 들어오는 세균, 바이러스, 먼지, 화분 등의 이물질에 대항하여 신체를 방어하는 중요한 림프기관
①palatine tonsil(구개편도): 구강과 인두사이 구개궁외측벽
②pharyngeal tonsil(인두편도): 인두의 후벽, 비대
③lingual tonsil(설편도): 설근주위
Mucosa-associated lymphoid tissue (MALT)..........In addition to the lymphoid tissue concentrated within the lymph nodes and spleen, lymphoid tissue is also found at other sites, most notably the gastrointestinal tract, respiratory tract and urogenital tract.
Gut associated lymphoid tissue (GALT,점막면역계, mucosal immune system, MALT).......장의 Peyer's patch, 맹장 (appendix)의 lymphoid follicle, 인후 (pharynx)의 tonsil, 상 부호흡기의 submucosal lymphoid follicle
This comprises:
tonsils, adenoids (Waldeyer's ring)
Peyer's patches
lymphoid aggregates in the appendix and large intestine
lymphoid tissue accumulating with age in the stomach
small lymphoid aggregates in the oesophagus
diffusely distributed lymphoid cells and plasma cells in the lamina propria of the gut
Large aggregates of GALT have distinct B cell follicles and T cell areas. Antigen presenting accessory cells are also present.
Peyer's Patches
These are quite large aggregates of lymphoid tissue found in the small intestine. The overlying 'dome' epithelium contains large numbers of intraepithelial lymphocytes. Some of the epithelial cells have complex microfolds in their surfaces. They are known as M cells and are believed to be important in the transfer of antigen from the gut lumen to Peyer's Patches. Peyer's Patches facilitate the generation of an immune response within the mucosa. B cell precursors and memory cells are stimulated by antigen in Peyer's Patches. Cells pass to the mesenteric lymph nodes where the immune response is amplified. Activated lymphocytes pass into the blood stream via the thoracic duct. These cells then home in the gut and carry out their final effector functions. HEVs are not present in Peyer's Patches and the mechanism by which cells home in on mucosal sites is unknown. Cell surface molecules known as addressins may have a role.

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