목차
Clinical and histopathological manifestations
A fluorescein angiogram of the left eye in a pt with PDR
Current appoaches to prevetion and treatment
Proposed pathogenic mechanisms and experimental therapies
Retinal anatomy and mechanisms of diabetic retinopathy
Proposed pathogenic mechanisms and experimental therapies
New diagnostic methods
Conclusion
A fluorescein angiogram of the left eye in a pt with PDR
Current appoaches to prevetion and treatment
Proposed pathogenic mechanisms and experimental therapies
Retinal anatomy and mechanisms of diabetic retinopathy
Proposed pathogenic mechanisms and experimental therapies
New diagnostic methods
Conclusion
본문내용
Clinical and histopathological manifestations
Earliest clinical sign of diabetic retinopathy
:microaneurysm, small outpouching from retinal capillaries and dot intraretinal hemorrhages
:all(type 1), 80%(type 2)-20years
Preproliferative retinopathy
:have increase in the number and size of intraretinal hemorrhages(cotton-wool spots)- indicate regional failure of retinal microvascular circulation(ischemia)
Clinical and histopathological manifestations
Proliferative retinopathy
:formation of new blood vessels->ominous prognosis for vision
New vessels
can extend into vitreous cavity,
hemorrhage into vitreous, resulting in visual loss,
can cause tractional retinal detachments from the accompanying contractile fibrous tissue
Late in the course of ds, new vs may form within the stroma of iris and may extend into ant chamberblocks outflow of the aqueous humor, causing neovascular gloucoma(elevation of intraocular pr)
:50%(type 1), 10%(type 2) - 15years
Earliest clinical sign of diabetic retinopathy
:microaneurysm, small outpouching from retinal capillaries and dot intraretinal hemorrhages
:all(type 1), 80%(type 2)-20years
Preproliferative retinopathy
:have increase in the number and size of intraretinal hemorrhages(cotton-wool spots)- indicate regional failure of retinal microvascular circulation(ischemia)
Clinical and histopathological manifestations
Proliferative retinopathy
:formation of new blood vessels->ominous prognosis for vision
New vessels
can extend into vitreous cavity,
hemorrhage into vitreous, resulting in visual loss,
can cause tractional retinal detachments from the accompanying contractile fibrous tissue
Late in the course of ds, new vs may form within the stroma of iris and may extend into ant chamberblocks outflow of the aqueous humor, causing neovascular gloucoma(elevation of intraocular pr)
:50%(type 1), 10%(type 2) - 15years
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