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toxin productive germs spores must heat above of minimum 120℃ 4 minutes and spores of E toxin productive germs becomes extinct when above of the several minutes boils. 1. Introduction
2. What is Clostridium botulinum?
3. The Botulinum Toxin
4. Toxins Action
5. Food-borne Botulism
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botulinum toxin type A for human treatment. In: Jankovic J, Hallet M, eds. Therapy With Botulinum Toxin. New York, NY: Marcel Dekker Inc; 1994:41.
Coffield JA, Considine RV, Simpson LL. The site and mechanism of action of botulinum neurotoxin. In: Jankovic J, Hallet M, eds. Therapy With Botulinum T
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botulinum toxin)가 주성분인 의약품이다
3) 보툴리눔 독소는 단백질의 한 종류. 분자량이 약 50킬로달톤 정도 되는 단백질이 분자량이 약 100킬로달톤 정도 되는 단백질과 이황화(disulfide) 결합으로 연결된 것이다
1-2 역사
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본문내용
What is Botulism?
Serious paralytic illness, caused by a nerve
toxin that is produced by the bacterium
Clostridium botulinum.
Three main kinds of botulism.
- borne botulism.
- Wound botulism.
- Infant botulism.
Characteristics
A gram positive,
obligate anaerobic,
spore-forming
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Toxin(탄저균)
② Bordetella pertussis Toxin(백일해균)
③ Clostridium botulinum Toxin(볼툴리누스균)
④ Clostridium perfringens(welchii) Toxin(가스괴저병)
⑤ Vibrio cholera Toxin(콜레라균)
3.진균독
⑥ Claviceps Toxin(맥각균)
⑦ Ochratoxin(오크라톡신)
⑧ Patulin(파툴린)
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