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목차
1. Introduction
2. Chemistry
2.1. Synthesis
2.2. Physico-Chemical Properties
3. Applications in Bone Tissue Engineering
3.1. Porous PLGA-HA Scaffolds
3.2. Fibrous Scaffolds
3.3. Hydrogels
3.4. Injectable Microspheres
4. Current Trends in the Development of Functionalized PLGA Constructs
5. Conclusions and Future Prospects
2. Chemistry
2.1. Synthesis
2.2. Physico-Chemical Properties
3. Applications in Bone Tissue Engineering
3.1. Porous PLGA-HA Scaffolds
3.2. Fibrous Scaffolds
3.3. Hydrogels
3.4. Injectable Microspheres
4. Current Trends in the Development of Functionalized PLGA Constructs
5. Conclusions and Future Prospects
본문내용
▪ Bone tissue engineering
- A research field with many clinical applications
- Bone replacement in the case of orthopaedic defects, bone neoplasia and tumours, pseudoarthrosis treatment,
stabilization of spinal segments, maxillofacial, craniofacial, orthopaedic, etc
▪ Scaffolds
- The strategy of designing synthetic bone substitutes
➡ For healing diseased or damaged bone tissue
➡ Promising alternative ; allografts, autografts, and xenografts
- Should be based on biomaterials with adequate properties
➡ For bone repair
➡ Biocompatibility, bioactivity, osteo-conduction, osteo-induction, and biodegradation
▪ Materials 1) Metals : Suitable for load-bearing applications
(∵ their favourable mechanical properties)
2) Ceramics : Excellent biocompatibility
: The chemical composition result that resembles the mineral phase of bone tissue
➡ However, Both metals and ceramics are generally poorly degradable
- A research field with many clinical applications
- Bone replacement in the case of orthopaedic defects, bone neoplasia and tumours, pseudoarthrosis treatment,
stabilization of spinal segments, maxillofacial, craniofacial, orthopaedic, etc
▪ Scaffolds
- The strategy of designing synthetic bone substitutes
➡ For healing diseased or damaged bone tissue
➡ Promising alternative ; allografts, autografts, and xenografts
- Should be based on biomaterials with adequate properties
➡ For bone repair
➡ Biocompatibility, bioactivity, osteo-conduction, osteo-induction, and biodegradation
▪ Materials 1) Metals : Suitable for load-bearing applications
(∵ their favourable mechanical properties)
2) Ceramics : Excellent biocompatibility
: The chemical composition result that resembles the mineral phase of bone tissue
➡ However, Both metals and ceramics are generally poorly degradable
키워드
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