위궤양 Gastric ulcer

목차

1. Etiology and pathogenesis

2. Clinical feature

3. Benign VS malignant

4. Course

5. complication of peptic ulcer

6. consequence ulceration

7. stress ulcer and erosion

8. drug induced ulcer and erosion

본문내용

이후에 발생
* curling's ulcer: burn
*cushing's ulcer: intracranial injury, IICP(뇌종양,SDH)
(위산 분비 증가와 관련)
8. drug induced ulcer and erosion
1) Aspirin
→ acetaminophen으로 바꾼다.
2) NSAID
·Risk factor for NSAID-induced mucosal injury
(1) older age
(2) female age
(3) High NSAID use
(4) protracted use of NSAID
(5) combined use of NSAID and glucocorticoids
(6) severe intercurrent illness
(7) unproven: H.pylori, smoker, caffeine, alcohol
·기전: (1) 위점막에 direct toxic
(2) PG 합성 억제→ 위점막 방어벽 손상(→back diffusion)
·예방: misoprostol(PGE1 analogue)
3) 기타
steoid, alcohol, colchicine, phenylbutazone, tolbutamide......

키워드

위,   gastric,   위산,   점막,   수술,   탄수화물