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Tumor peptides, fragments of tumor proteins recognized by T cells
. Dendritic Cells are isolated from the blood, exposed to tumor peptides or engineered to produce tumor proteins and then reinjected.
. Gangliosides produce antibodies to these molecules found on the surface of tumor cells. Genes cod
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genetics NATURE, VOL. 411, 336-341 (2001)
2. Biology Of Cancer, Robert A. Weinberg. 2006
3. AndreaI. McClatchey. Merlin and ERM proteins: unappreciated roles in cancer
development? NATURE, VOL. 3, 877-883(2003)
4. K. Cichowski, T. Jacks. NF1 Tumor Suppressor Gene FunctionNarrowing the GAP.
Cell, Vo
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tumorigenesis
Change of chromatin structure
Silencing of tumor suppressor gene(p53)
Reactivation of tumorigenesis genes(angiogenic factor)
Tumorigenesis
HDAC 결합인자
Mi-2β(chromatin remodeling factor)
MTA(metastasis-associated factors)
HAT,HDAC mechanism
HDAC isotypes
Class I - Rpd3 와
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tumor suppressor genes. Int J Cancer 2007, 121, 2693-702.
5. S.J.Flint et al. Principles of virology, third edition. ASM press 2009, Vol 1, 520-523.
6. 류왕식. 바이러스학. 라이프사이언스 2007, 121-128. 1. SV40이란?
2. SV40의 구조
3. SV40의 특성
4. infection cycle
5. 진단방법
6. R
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암
암의 발생
Telomere and Telomerease activity
대상 유전자
Tumor Suppressor gene
P53 DNA binding
P53 gene
p53 protein
작용기전
P53 mutation
reference 암
암의 발생
Telomere and Telomerease activity
대상 유전자
Tumor Suppressor gene
P53 DNA binding
P53 gene
p53 protein
작
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suppressor genes: inhibitory constraints on the storage of long-term memory. Science. 279: 338341.
73. Murphy, K.J. and Regan, C.M. (1998). Neurobiol Learn Mem. 70: 73;
Roullet, P., Mileusnic, R., Rose, S.P.R., Sara,S.J. (1997). NeuroReport 8: 1907.
74. Emptage, N.J., and Carew, T.J. (1993). Scien
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