목차
목 차
1. 서론--------------------------------------- 1
2. 산화적 스트레스와 노화------------------------ 4
3. 활성산소 관련 각종 질환------------------------- 7
4. 항산화제------------------------------------ 11
5. 천연항산화제 개발 연구------------------------ 16
6. 항산화제의 효과------------------------------- 19
7. 결 론--------------------------------------- 22
8. 참고문헌 ------------------------------------ 23
1. 서론--------------------------------------- 1
2. 산화적 스트레스와 노화------------------------ 4
3. 활성산소 관련 각종 질환------------------------- 7
4. 항산화제------------------------------------ 11
5. 천연항산화제 개발 연구------------------------ 16
6. 항산화제의 효과------------------------------- 19
7. 결 론--------------------------------------- 22
8. 참고문헌 ------------------------------------ 23
본문내용
dicals in the origination and evolution of life, aging, and disease processes, Pp. 3-49. In Johnson, Jr., J. E. R. Walford, D. Harmon and J. Miquel(ed.), Free radicals, aging and degenerative disease, Alan R. Liss, New York.
18. Johnson, K. J., A. Rehan and P. A. Ward. (1988) The role of oxygen radicals in kidney disease. In Halliwell, B.(ed.), Proceedings of the Upjohn Symposium on oxidants and Disease. Allen Press, Kansas.
19. Kedziora, J. and G. Bartosz. (1988) Downs syndrome: a pathology involving the lack of balance of reactive oxygen species. Free Radical Biol. Med. 4: 317-330.
20. Kim, W. G., J. P. Kim, H. Koshino, K. Shin-Ya, H. Seto and I. D. Yoo (1997) Benzastatin E, F, and G : new indoline alkaloids with neronal cell protecting activity from Streptomyces nitrosporeus. Tetrahedron 53: 4309-4316 (1997)17. Kim, W. G., J. P. Kim, and I. D. Yoo. (1996) Benzastatin A, B, C and D: New free radical scavengers from Streptomyces nitrosforeus 30643. (II) Structure determination. J. Antibiotics 49: 26-30.
21. Lee, I. K., C. J. Kim, K. S. Song, H. M. Kim and I. D. Yoo. (1995) Two more benzylated dihydroflavonols from Cudrania tricuspidata. J. Natural Products 58: 1614-1617.
22. Massie, H. R., D. R. Aiello and T. J. Doherty. (1984) Dietary vitamin C improves the servival of mice. Gerontology 30: 371-375.
23. Marnett, L. J. (1987) Peroxyl free radicals: potential mediators of tumor initiation and promotion. Carcinogenesis 8: 1365-1373.
24. McBride, T. J., B. D. Preston and L. A. Loeb. (1991) Mutagenic spectrum resulting from DNA damage by oxygen radicals. Biochemistry 30: 207-213.
25. McCord, J. M. (1987) Oxygen-derived radicals: a link between reperfusion injury and inflammation. Fed. Proc. 46. 2402-2406.
26. Miquel, J., A. T. Quintanilha, H. Weber(ed.) (1989) Handbook of free radicals and antioxidants in biomedicine, Vol. I, CRC Press, Boca Raton, Florida.
27. Packer, L., (ed.). (1994) Meth. Enzymol. Vol. 233, Oxygen radicals in biological systems. Academic Press, San Diego.
28. Packer, L., (ed.). (1994) Meth. Enzymol. Vol. 234, Oxygen radicals in biological systems. Academic Press, San Diego. 30. Pecker, L., Glazer, A. N. (ed.). (1990) Meth. Enzymol. Vol. 186, Oxygen radicals in biological systems. AcademicaPress, San Diego. 31. Poli, G., E. Albano and M. U. Dianzani(ed.) (1993) Free radicals: From basic science to medicine, Birkhauser Verlag, Basel, Switzerland.
29. Sawyer, D. T. and J. S. Valentine. (1981) How super is superoxide? Acc. Chem. Res. 14: 393.
30. Wayner, D. D. M., G. W. Burton, K. V. Ingold, L. R. C. Barclay, S. J. Locke. (1987) The relative contribution of vitamin E, urate, ascorbate and proteins to the total peroxy radical-trapping antioxidant activity of human blood plasma. Biochem. Biophy. Acta 924: 408-419.
31. Yun, B. S., I.-J. Ryoo, W. G. Kim, J. P. Kim, H. Koshino, H. Seto and I. D. Yoo (1996) Structures of phenazostatins A and B, Neuronal cell protecting substances of microbial origin. Tetrahedron Letters, 37: 8529-8530.
18. Johnson, K. J., A. Rehan and P. A. Ward. (1988) The role of oxygen radicals in kidney disease. In Halliwell, B.(ed.), Proceedings of the Upjohn Symposium on oxidants and Disease. Allen Press, Kansas.
19. Kedziora, J. and G. Bartosz. (1988) Downs syndrome: a pathology involving the lack of balance of reactive oxygen species. Free Radical Biol. Med. 4: 317-330.
20. Kim, W. G., J. P. Kim, H. Koshino, K. Shin-Ya, H. Seto and I. D. Yoo (1997) Benzastatin E, F, and G : new indoline alkaloids with neronal cell protecting activity from Streptomyces nitrosporeus. Tetrahedron 53: 4309-4316 (1997)17. Kim, W. G., J. P. Kim, and I. D. Yoo. (1996) Benzastatin A, B, C and D: New free radical scavengers from Streptomyces nitrosforeus 30643. (II) Structure determination. J. Antibiotics 49: 26-30.
21. Lee, I. K., C. J. Kim, K. S. Song, H. M. Kim and I. D. Yoo. (1995) Two more benzylated dihydroflavonols from Cudrania tricuspidata. J. Natural Products 58: 1614-1617.
22. Massie, H. R., D. R. Aiello and T. J. Doherty. (1984) Dietary vitamin C improves the servival of mice. Gerontology 30: 371-375.
23. Marnett, L. J. (1987) Peroxyl free radicals: potential mediators of tumor initiation and promotion. Carcinogenesis 8: 1365-1373.
24. McBride, T. J., B. D. Preston and L. A. Loeb. (1991) Mutagenic spectrum resulting from DNA damage by oxygen radicals. Biochemistry 30: 207-213.
25. McCord, J. M. (1987) Oxygen-derived radicals: a link between reperfusion injury and inflammation. Fed. Proc. 46. 2402-2406.
26. Miquel, J., A. T. Quintanilha, H. Weber(ed.) (1989) Handbook of free radicals and antioxidants in biomedicine, Vol. I, CRC Press, Boca Raton, Florida.
27. Packer, L., (ed.). (1994) Meth. Enzymol. Vol. 233, Oxygen radicals in biological systems. Academic Press, San Diego.
28. Packer, L., (ed.). (1994) Meth. Enzymol. Vol. 234, Oxygen radicals in biological systems. Academic Press, San Diego. 30. Pecker, L., Glazer, A. N. (ed.). (1990) Meth. Enzymol. Vol. 186, Oxygen radicals in biological systems. AcademicaPress, San Diego. 31. Poli, G., E. Albano and M. U. Dianzani(ed.) (1993) Free radicals: From basic science to medicine, Birkhauser Verlag, Basel, Switzerland.
29. Sawyer, D. T. and J. S. Valentine. (1981) How super is superoxide? Acc. Chem. Res. 14: 393.
30. Wayner, D. D. M., G. W. Burton, K. V. Ingold, L. R. C. Barclay, S. J. Locke. (1987) The relative contribution of vitamin E, urate, ascorbate and proteins to the total peroxy radical-trapping antioxidant activity of human blood plasma. Biochem. Biophy. Acta 924: 408-419.
31. Yun, B. S., I.-J. Ryoo, W. G. Kim, J. P. Kim, H. Koshino, H. Seto and I. D. Yoo (1996) Structures of phenazostatins A and B, Neuronal cell protecting substances of microbial origin. Tetrahedron Letters, 37: 8529-8530.