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BIOCHEMISTRY 1
Chapter 4 Nucleic Acids
<KEY CONCEPTS>
▆ Components of Nucleic Acids
▆ Double-Helical Structure of DNA
▆ Gene Expression for Functional Molecules
▆ Genetic Codes
Ⅰ. Nucleic Acids의 구조와 기능
┗━━━━━━━━━━─────
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바이오학부 생물화학 (2011)
핵 산 (Nucleic Acids)
핵산 (Nucleic acids)
━━━━━━━━━━─────────…
● 유전자 발현 (Gene expression)
┌─────────────────────────
│ DNA → RNA → Protein
│
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Nucleic Acids / Chapman and Hall / 10th edition / 1995
- 이정주, 노현모, 김상구, 서봉모, 서동상 / 가드너 유전학 / 범한서적주식회사 / 개정 8판 / 1996
- C.W. Sensen / Essentials of genomics and bioinformatics / Wiley-VCH / 2002
인터넷 자료
- http://www.shingu.ac.kr/%7Edolchoi/lc_bc/
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Nucleic Acids Research, p.136
·Titli et al, 2018, Significance of circulatory DPP4 activity in metabolic diseases, IUBMB life, pp.112-119
·Sobierajska et al, 2014, Protein disulfide isomerase directly interacts with β-actin Cys374 and regulates cytoskeleton reorganization., Journal of Biological Che
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Nucleic Acids, Richard Durbin, S. Eddy, A. Krogh, G. Mitchison, 1998, Cambridge University Press
Human Molecular Genetics, Andrew P. Read, Tom Strachan, 1999, BIOS Scientific Publishers Ltd.
Genomes, T.A. Brown, 1999, BIOS Scientific Publishers Ltd.
DNA Microarrays: A Practical Approach (Practical A
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Nucleic Acids Res., pp 881-882
·S. S. Freitas, J. et al, 2008, Optimization of Isopropanol and Ammonium Sulfate Precipitation Steps in the Purification of Plasmid DNA, Biotechnology progress, 1179-1186
·Jinlin et al, 2006, Identification of a glycine-rich protein from the tick Rhipicephalus haemaphy
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Ⅰ. Introduction
1) Bioinformatics와 실험 목적
Bioinformatics란, 생명체의 정보를 이용해서 다양한 분자생물학적인 기작들을 밝히고 이를 바탕으로 질병의 원리, 혹은 치료 타겟을 발굴하는 학문이다. 여기서 정의하는 ‘생명체의 정보’는 굉장히 다
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980, p 6380.
<5>, <6> M.J. Waring , "Complex formation between ethidium bromide and nucleic acids.", Journal of Molecular Biology 13 , 1965, (1): p 269282.
<7> Albert A-C, Spirito F Figueroa-Bossi N, Bossi L Rahmouni AR, "Hyper-negative template DNA supercoiling during transcri
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nucleic acids)하고 결합해서 nucleic acid-CTAB complex를 만듦. 원심분리를 하게 되면 nucleic acid-CTAB complex가 침전.
(3)DEPC (diethyl pyrocarbonate)
histidine을 선택적으로 alkylation시키는 물질. 대부분의 RNase들의 active site에는 Histidine이 있고 따라서 DEPC는 효과
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acids
Lipids containing glycerol
Lipids not containing glycerols
Isoprenoid
Lipoproteins
Proteins
Amino acids
Absorption spectra
Analysis of amino acid mixtures
Purification of Proteins
Carbohydrates Cn(H2O)n
Nucleic acids
Vitamins
#Enzymes
History of enzymes
Classification of Enzym
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